atf3 inducer Search Results


atf3 inducer 1  (MedChemExpress)
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MedChemExpress atf3 inducer 1
A The appearance of femoral heads in control, GIONFH model (Dex), and <t>ATF3</t> inducer 1-treated groups. B HE staining of femoral heads in three groups and quantitative analysis of the results of HE staining (n = 5 technical replicates). C IHC staining of ALP, OCN and COL1 in three groups and quantitative analysis of immunohistochemical positive expression in each group of mice. (n = 3 technical replicates). D The appearance of femoral heads in ATF3 inducer 1-treated WT and Ptx3 -KO groups. E HE staining of femoral heads in both groups and quantitative analysis of the results of HE staining (n = 5 technical replicates). F IHC staining of ALP, OCN and COL1 in both groups and quantitative analysis of immunohistochemical positive expression in each group of mice. (n = 3 technical replicates). Statistical analysis: Dunnett’s post-hoc tests. Error bars: standard deviation, SD. Control: vehicle-treated, n = 5; Dex: GIONH model, n = 5; Dex+ATF3/ Ptx3 +/+ +ATF3: GIONFH model with 40 mg/kg ATF3 <t>inducer</t> <t>1</t> administration twice a week, n = 5; Ptx3 −/− +ATF3: Ptx3 -knockout mice with GIONFH modeling and ATF3 inducer 1, n = 5. Red arrows: empty lacunae; Black arrows: trabecular bone disruption; Star symbol: necrotic bone marrow; White arrows: positive cells. The images provided in all figures represent typical examples from each experimental group.
Atf3 Inducer 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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A The appearance of femoral heads in control, GIONFH model (Dex), and ATF3 inducer 1-treated groups. B HE staining of femoral heads in three groups and quantitative analysis of the results of HE staining (n = 5 technical replicates). C IHC staining of ALP, OCN and COL1 in three groups and quantitative analysis of immunohistochemical positive expression in each group of mice. (n = 3 technical replicates). D The appearance of femoral heads in ATF3 inducer 1-treated WT and Ptx3 -KO groups. E HE staining of femoral heads in both groups and quantitative analysis of the results of HE staining (n = 5 technical replicates). F IHC staining of ALP, OCN and COL1 in both groups and quantitative analysis of immunohistochemical positive expression in each group of mice. (n = 3 technical replicates). Statistical analysis: Dunnett’s post-hoc tests. Error bars: standard deviation, SD. Control: vehicle-treated, n = 5; Dex: GIONH model, n = 5; Dex+ATF3/ Ptx3 +/+ +ATF3: GIONFH model with 40 mg/kg ATF3 inducer 1 administration twice a week, n = 5; Ptx3 −/− +ATF3: Ptx3 -knockout mice with GIONFH modeling and ATF3 inducer 1, n = 5. Red arrows: empty lacunae; Black arrows: trabecular bone disruption; Star symbol: necrotic bone marrow; White arrows: positive cells. The images provided in all figures represent typical examples from each experimental group.

Journal: Communications Biology

Article Title: Pentraxin 3 ameliorates glucocorticoid-induced osteonecrosis of the femoral head via TLR4/NF-κB/FGF21 signaling axis

doi: 10.1038/s42003-025-09282-3

Figure Lengend Snippet: A The appearance of femoral heads in control, GIONFH model (Dex), and ATF3 inducer 1-treated groups. B HE staining of femoral heads in three groups and quantitative analysis of the results of HE staining (n = 5 technical replicates). C IHC staining of ALP, OCN and COL1 in three groups and quantitative analysis of immunohistochemical positive expression in each group of mice. (n = 3 technical replicates). D The appearance of femoral heads in ATF3 inducer 1-treated WT and Ptx3 -KO groups. E HE staining of femoral heads in both groups and quantitative analysis of the results of HE staining (n = 5 technical replicates). F IHC staining of ALP, OCN and COL1 in both groups and quantitative analysis of immunohistochemical positive expression in each group of mice. (n = 3 technical replicates). Statistical analysis: Dunnett’s post-hoc tests. Error bars: standard deviation, SD. Control: vehicle-treated, n = 5; Dex: GIONH model, n = 5; Dex+ATF3/ Ptx3 +/+ +ATF3: GIONFH model with 40 mg/kg ATF3 inducer 1 administration twice a week, n = 5; Ptx3 −/− +ATF3: Ptx3 -knockout mice with GIONFH modeling and ATF3 inducer 1, n = 5. Red arrows: empty lacunae; Black arrows: trabecular bone disruption; Star symbol: necrotic bone marrow; White arrows: positive cells. The images provided in all figures represent typical examples from each experimental group.

Article Snippet: The impact of rPTX3 (HY- P73714 , MCE, USA) and ATF3 inducer 1 (HY-151923, MCE, USA) on cell viability was assessed using the CCK-8 assay (ApexBio), following the protocol provided by the manufacturer.

Techniques: Control, Staining, Immunohistochemistry, Immunohistochemical staining, Expressing, Standard Deviation, Knock-Out, Disruption